Health, Aging, and Disease - It's all About Energy - Part 1
YouTube video by Dr. Frank Shallenberger (https://www.youtube.com/watch?v=E2-Plq-mcqA). Transcript is the auto-caption track — verbatim ASR, not a certified transcript.

hi I'm Frank shenberger I'm uh I'm a medical doctor I head up the Nevada Center for alternative and anti-aging medicine in Carson City Nevada and I've been practicing medicine for going on 40 years now uh most of that time in excess of 30 years I've devoted to the study of alternative medicine um you can also hear that referred to as integrative medicine or biological medicine or natural medicine basically it's it's when doctors focus on helping uh the patients innate healing tendencies in the patient's body to heal the body itself uh the Creator when he created our bodies U did it with a with a divine plan that allows our bodies to heal themselves in other words our bodies are able to diagnose whatever condition whatever disease whatever ailment is affecting us and to create conditions in the body where in the body will actually literally heal itself of that disease or condition and and what we as as natural alternative Physicians do is work with the patient's body to find out exactly what what we need to do to help that body heal itself of all the things that I can do to help my patients bodies heal themselves singularly by far the most important is to improve the way their bodies produce energy and so uh uh we produced this uh four-part uh video uh lecture series that is going to go into exactly that how uh how your body produces energy how that affects your health how it can make you sick when you don't produce energy adequately how it will make you well when you do produce energy adequately what you can do to maximize your energy production and very importantly how you can in fact measure your energy production so you can know if you've got a problem uh in this regard long before it actually happens so uh the title of this series is Health aging and disease it's all about energy and this is part one the importance of cellular energy production um this is the this is a uh the book on the the four-part series that we're going to do uh part two is maximizing your cellular energy production part three is measuring cellular energy production uh with bioenergy testing it's a testing device that uh uh I developed a few years ago and part four is how to use biological or bioenergy testing to maximize your health and to slow down aging uh this series this lecture series is going to be uh devoted mostly to uh professionals we're going to get into a little chemistry um however I found over the years that uh the way I present this information is is typically handled very well by lay people as well so so I think all people will will see some benefit out of this that certainly is my hope uh I have written two books which are currently available uh you know at all the major book Outlets one's called bursting with energy and the other's called called the type 2 diabetes breakthrough they're both about energy production diabetes would be an example a great example of a chronic disease that is 100% caused by decrease in energy production and is 100% prevented and healed by improving energy production so that's why I wrote that book but you can get the gist and a lot of particulars and all the references that you're going to hear on this lecture Series in those books so let's start off and and let's just uh uh look at something that is is is very basic and that is that energy production is at the center of literally everything that happens in your body energy production is by far in a way the most critical uh you know if you stop drinking water you'll do all right for a well if you stop eating you'll do all right for a while if you stop bathing you might not smell too good but you'll do all right for a while but if you stop producing energy you will die in 2 to 3 minutes that's how fundamental energy production is to your health and what this slide shows is is that um everything is dependent on energy whether it's the fun every one of your organs depends on energy production or work even your senses uh your repair system so that if you break your leg or you injure a part of your body your ability to repair it 100% depend dep on your energy systems even your thoughts so conditions say as depression uh especially attention deficit disease bipolar disorders all those kinds of conditions of thoughts are conditions primarily of energy deficiency uh the ability for the body to digest uh how about elimination and detoxification all the toxins that you get exposed to are only eliminated one way and that is through energy production and we'll look into about how all these things are factors here in the in the next few parts of this lecture series but just understand that energy production is at the center of everything there is nothing that your body does it isn't 100% dependent on energy you can't say that about any vitamin you can't say that about any food you can't even say that about any hormone uh and that's why it's so critically important so what is health well a lot of people think that health is just the absence of symptoms I feel good so I must be healthy uh or a lot of other people say you know I went to my doctor he told me I didn't have a disease so I must be healthy uh or he you know he did he did a bunch of tests on me my cholesterol and my blood sugar and all my tester normal so I must be healthy uh but the truth is health is not the absence of anything it doesn't mean just because you don't have abnormal tests or just because you don't have symptoms you're not really healthy uh he health is not the absence of anything it's the presence of something and that something is energy and you're as healthy as your amount of energy you can produce if you can produce optimal amounts of energy then I would call you optimally healthy if you could produce suboptimal amounts of energy then that's about how good your health is too uh Health how how do you know if you're healthy then if you can't tell by just an absence of symptoms or normal blood test and know well health is the presence of optimal cellular energy production and the reason that is is because it's one thing we've just said is that every biochemical and physiological reaction is dependent on cellular energy production making it the most Global biomarker for health there's nothing that is singularly as dependent on any on on the way your body functions as how well it produces energy so it's the most Global biomarker for health also cellular energy production is affected by everything else so energy production is affected by everything that goes on in your body from stress to how you eat uh and everything that goes on your body is affected by cellular energy production so health and cellular energy production are basically one and the same thing and finally decreased cellular energy production occurs long before any sign or symptom of disease and that's what we're going to go over today in just a few minutes and I'm going to show you that just because you don't have any symptoms just because you feel well just because your doctor told you your your your lab tests were within normal limits doesn't mean that you're producing energy on a cellular basis as well as you could be and that's what's necessary to prevent disease maximize your health and even slow down the aging process uh so what are diseases then so you probably figured this out by now U diseases according to the dictionary are just the names that are given to various pathological conditions in the body in which the organs or the regulating systems of the body become dysfunctional or don't work uh the pathology of all chronic degenerative disease the thing that causes all those diseases to process to happen is the direct result of free radical injury most of you have heard of free radicals they're special molecules that uh that are produced during energy production that actually end up destroying the body so that's how we get these diseases through free radical production and what I want you to understand right from the get-go is that free radical production is caused by only one thing and that is impaired cellular energy production so if you are optimally producing energy in your cells you will be producing the minimal amounts of free radicals that your body requires but to the degree that your cells are not optimally producing energy you're going to be producing many more free radicals than you should be ideally and that's what's going to cause your body to ultimately break down and for you to get sick so Health it's the presence of cellular energy production disease it's the consequence of not having adequate cellular energy production so you know during the course of this lecture series I'll I'll use a number of terms they all really refer to the same thing um cellular energy production that's the amount of energy produced in the cells is produced in a part of the cells called the mitochondria so every cell has thousands of mitochondria there little areas in the cell where oxygen is processed into energy we're going to go over all of this in the lectures to come um so cellular energy production is really the same as mitochondrial function which is the same as mitochondrial efficiency which is the same as oxidation efficiency which is the same as oxidation potential so these are all terms that scientists and doctors use all referring to the same basic thing which and for the most part I'll be referring to in this series as cellular energy production so that's the little mitochondria that's an example of the mitochondria and uh we won't spend much time here probably you're thinking that's a good thing uh but this just shows you this slide shows you that that uh today scientists are able to map out what goes on in the mitochondria to a very very uh uh detailed extent and um and these show the various biochemical processes that go on and fundamentally what I can tell you is right over here is uh oxygen and right over here is water and what's happening in this mitochondria is that oxygen which is one of the highest most energy energy dense molecules in the universe is converted into water which is the lowest energy molecule in the universe you got high energy molecule converted to low energy molecule the result is a release in energy and it's through this complex system in the mitochondria here that your body is able to harness that energy and then use it in the cell for the cell to do every single one of the things that the cell can do as long as your mitochondria can effectively process this oxygen you're going to be producing lots of energy you're going to be producing it efficiently your cells will work well you'll be at Optimal Health but as soon as that mitochondria can't produce energy from that oxygen efficiently what's going to happen is excessive production of free radicals and destruction of your tissues and of course decrease energy production along efficiency next few slides are going to kind of go into to some of the scientific literature I'll probably go through these kind of fast um uh but these are all available uh uh you know through any library or through PubMed uh you can get all this information this particular slide comes from a friend of mine's name is war deed who uh wrote one of the Premier books on aging and degenerative disease and what Ward pointed out is that nothing is as consistent as predictable as the gradual linear decline in mitochondrial functions that we see in all aging populations so here's a 30-year-old person we typically look at 30 years old as being the age at which your cells are able to produce energy with maximum efficiency and this is what happens as you get older and if you come down here to around the 70y old person you can see that roughly speaking the energy production is cut in half of what they were in the prime of their life so what we would like to do and what's possible and what you're going to learn in this lecture series is how to flatten this this curve out so that instead of energy production going down in a very linear and predictable way it stays pretty much flat now is that possible yes it's definitely possible how do I know because for the last 10 years I've been measuring energy production we have a system and you're going to learn about this a way to measure cellular energy production in my patients and I can tell you I have a lot of patients in fact I have one gentleman who's 80 years old and instead of his energy production being up here his energy production is right here around the lines of a typical someplace um I'm 62 years old that would put me right here but my energy production is as good as the average 30 years old so my energy production is up there we'll talk about how you can do that for yourself these are just some articles some Premier articles uh that have been published uh this one from the proceedings of the National Academy in 1998 uh again the same proceedings of the National Academy in 2002 what these articles basically say is impaired mitochondrial function plays the major role in the entire aging process so if you want to age gracefully if you want to have full function as you get older what you want to do is keep your cellular energy production at a maximum down here it says cellular processes affected by impaired cellular energy production include name something basically and this is kind of reminiscent of the first slide we saw your ability to detoxify to repair to uh replicate your DNA to maintain the balance of water your your body and all the higher order processes such as cognitive function the way your brain works all of these things are dependent on energy production now this is a um a slide that uh is just fantastic to me this comes out of a uh magazine called nature this was published in 2004 and this definitely proves my point and uh so what they did here in this slide is the scientists genetically modified some mice and they took the mice and divide them in two groups half the group they modified these mice so that their cells could not produce energy as efficiently as the other half and then they just watched what happened as these mice lived out their life well predictably the mice that couldn't produce cellular energy as well had a significantly reduced lifespan they also had a premature onset of all the age related phenotypes that means all the stuff that happens to us as we get older that we don't like uh such as loss of lean body mass alopecia means hair falling out kyphosis means osteoporosis and bending over all that stuff that we see with older people anemia reduced fertility heart failure all the the things that you would expect to see in somebody as they age were dramatically increased in these mice because they couldn't produce cellular energy efficiently same thing happens to us and the authors concluded on the bottom here these results provide a positive link between decreased mitochondrial function and aging basically they're telling you this is what causes your body to age now there's another study that uh was very similar to that and kind of looks at it at different way uh but but again this study also came out in 2004 in a magazine called the Aging cell um and what what these scientists did uh is they didn't genetically modify anything they just took a bunch of mice and they used the technology it's not the same as the one I use but a different kind of technology to determine how the cellular uh energy production was in these mice and what they noted was uh that some mice produce cellular energy production very effici L uh in our today's terminology we would call them fast oxidizers and somewhere in part three I'm going to go over the whole concept of fast and slow oxidizers with you but some of these mice were what we call fast oxidizers meaning they produced energy very efficiently and some of the mice were on the other end of the spectrum and we call them slow oxidizers where they did not produce cellular energy as efficiently and what they did is they just followed them over the course of a lifetime and the results were extremely dramatic and established an association between longevity and individual variations in energy production because what they found was that the mice that in the higher quartile of mitochondrial function in other words the mice that were in the quarter of the mice that produced the most resting energy cellular energy production lived the full 30% longer than the mice in the lowest cortile now that's astounding almost 40% longer simply from one thing and that is improved resting cellular energy production as you will see in the rest of this lecture series we can measure that so we can tell you what cortile you're in if you're in the lowest cortile we can then tell you how world um we're going to talk a little bit I think it's in the second part of this lecture series on how how uh cells actually uh create the free radicals I alluded to that a little bit but how cells create the free radicals that cause our bodies to age but I did want to mention this study uh that was published in 1994 again from the proceedings of the National Academy of Sciences and uh in this study I'll just quote the authors say oxidants generated by mitochondria appear to be the major source of oxidative lesions that accumulate with age so that's where you're getting all those free radicals is from the mitochondria and then they go on these these lesions that cause the aging process related deficits in the mitochondrial function which are associated with a general physiological decline known as aging basically what they're telling you right there is that the reason we age and will age is because we'll produce free radicals and the more efficiently our mitochondria process oxygen to produce energy the less free radicals will produce the longer we'll live and the better our quality of life now I'm going to really scoot over these next few studies very quickly I just wanted to prove a point and that is if you go to any of the medical databases and you plug in uh decreased mitochondrial function or decreased cellular energy production and the name of a disease just name any disease you'll see that there's already many articles written about the association between mitochondrial function and those diseases so I'm just going to run through these slides very quickly and just to kind of make a point and this is only a small sampling of what's available out there so here's one about mitochondrial function causing osteoporosis here's one about age related macular degeneration being caused by decreased mitochondrial function uh here's one about blood pressure being caused by decreased mitochondrial function this article here is about rheumatoid and all the reactive arthritis being caused by decreased mitochondrial function this one here is about cancer being caused by decreased mitochondrial function actually warberg won the Nobel Prize in the 1930s for just that point showing that cancer was a direct result of decreased mitochondrial function and of course diabetes I alluded to that and my my more recent book is all about that uh also Parkinson's disease caused by decreased mitochondrial function as is Alzheimer's disease the same thing heart failure there's a resurgence a heart failure these days nobody quite knows exactly why but certainly you can bet that the primary lesion for the increase in heart failure has to do with decreased mitochondrial function or decreased cellular energy production and uh uh this is all conditions of the heart from coronary artery disease to arhythmia all of this primarily caused by decreased mitochondrial function and there are many more articles exactly like that that would go on to say the same thing about any name now before we get into the next topic I just want to uh uh be clear on one thing that's often misunderstood I've been using the term cellular energy production and that's the way your cells produce energy uh but I want you to know that that's different than feeling energetic feeling energetic is another another another issue entirely so that you can have very poor cellular energy production and actually feel energetic and uh conversely you can have excellent cellular energy production and feel tired and run down let me give you an example how that would work let's take a premier athlete uh let's take Lance Armstrong for example um I'm not tested Armstrong but would be a pretty easy to say that his cellular energy production is is at an all-time high and yet if he didn't get enough sleep if he was overly stressed uh if he overtrained he may very likely be be complaining of fatigue and tiredness and weariness uh on the other end of the spectrum we see a lot of people uh who have very poor cellular energy production uh but uh can have decent energy levels that mean they feel pretty good so they're two different topics and two different things and yes it's true if you have poor cellular energy production ultimately it will lead to you feeling tired and run down but there can be a long period of time where you actually feel quite good and that's what takes us into this next concept which is the concept uh of early onset mitochondrial dysfunction this is a term that uh I developed and we just abbreviate it so I have to say all that long phrase uh eomd eomd stands for early onset mitochondrial dysfunction what it means is is is very simple actually it refers to a deterioration of the mitochondrial function or deterioration of cellular energy production that commonly occurs in the young and asymptomatic and increases with age so it can start early and it gets worse as you age this is the name of the condition so we're again to reiterate talking about a condition where the mitochondria are not producing energy well which decreased cellular energy production and this can onset so let's just ask this question uh are is a person healthy or are they just not sick I'm here to tell you eomd is for Real here's a study that we published a couple few years back where we took 50 subjects now these subjects were randomly selected as they presented to a number of different clinics uh these subjects who were between the ages of 20 and 40 years old so they're young uh they were asymptomatic which means that they weren't complaining of anything they felt great they were healthc conscious because the only reason they showed up to have their cellular energy production tested was because they were health conscious they wanted to make sure their cellular energy production was good and uh these were a group of young people from all over the world namely from clinics in Carson City Los Angeles Grand Junction Colorado and Singapore and here's what we found out in these 50 subjects 54% of them had normal mitochondrial function so that's what you'd expect right you expect young people who feel great should have normal cellular cellular energy output but that was only 54% of them all the rest had decreased cellular energy production and I find that amazing we're talking about healthy health conscious these are exercisers by the way uh young people and almost half of them are already showing that their ability to produce energy on a cellular level is starting to become compromised but let's break it down because it's even gets worse when we broke it down broke that 46% down to see you know how bad do they get in fact 36% of them had less than 90% of what would have been predicted or what would have been considered a normal cellular energy production 26% of them had less than 80% of what they had should have had 12% of them 12 out of every hundred young people who feel great had less than 60% almost half of what they should have been coming up with so these people all of these people here have what I call early onset mitochondrial dysfunction eomd now the the last thing on here to notice is going to turn out to be very important because of all the subjects that had normal healthy cellular cellular energy production none of them had impaired fat metabolism on the other hand every single one of the young people who had a deficit in their cellular energy production every single one had an impairment of their fat metabolism we're going to talk talk very much about that because this is critical to understanding how things go wrong how things went wrong with these young people and how things can go wrong with you and I so early onset mitochondrial dysfunction decrease in cellular energy production in the young in the asymptomatic it happens and it not only happens but it's very common and it doesn't give you any warning system and it's going on right now and a lot of you people that are listening to me talk right now and you'd have no idea what going on if you weren't able to test it and fortunately we are able to test it we'll be talking about how that testing process happens in some of the later lectures so what's the cost of having that problem what's the cost of having eomd here's just a partial list this just comes from the literature you you don't synthesize your DNA and RNA as well you don't synthesize protein enzymes and hormones as well you can't maintain your cell membrane potential this turns out to be a big problem uh you you have accelerated cell death and cell loss you're aging faster you have an decreased intracellular hydration your skin and the rest of your body tends to become dehydrated you have increased free radical damage we already mentioned that you you your brain isn't going to work as well as it should work you have decreased ability to throw off toxins this is huge because we live in a world that's just filled with toxins and if our ability to uh remove toxins from the body is compromised in any way shape or form this can dramatically lead to illness and finally you have a condition called mitochondrial Decay mitochondria Decay is different than uh eomd eomd just means that the mitochondria aren't working that well mitochondria mean Decay means they're dead they've been destroyed uh so all of that aging and degenerative disease these are all what eomd leads to so yes it's important to be able to diagnose that and to find out how to treat that I just mentioned this concept of mitochondrial Decay and so I kind of go over a little bit about again what the main difference is uh e just refers to deterioration in the mitochondrial function mitochondrial produce a molecule called ATP and eomd means they don't do that very well uh whereas mitochondrial Decay means that the mitochondria have actually been destroyed eomd is reversible it can be fixed where's mitochondrial Decay can't once your mitochondria destroyed you're not getting them back at least not so far with what we know eomd occurs in young and healthy people but you're not going to see mitochondrial decay in young and healthy people that's something that comes along around the sixth or seventh decade but it starts with eomd starts with EMD eomd leads to mitochondrial Decay by the and so the the idea is don't wait until you actually get mitochondrial Decay to think gez maybe I better start doing something about my energy production find out about it early before you it leads to mitochondrial Decay because eomd is what causes it and by diagnosing and treating eomd you can prevent mitochondrial Decay and the disease and the increase in the aging process that it leads to we're going to go into this in Greater detail in the third lecture where we talk about what to do about all this stuff um but there are 10 causes of eomd that I've been able to identify let's just take a look at them uh some of these are causes that happened before the oxygen actually gets to the mitochondria these are factors that have to do with not the actual mitochondrial function itself and these are factors that have to do with how the actual mitochondria are functioning uh you can kind of think of Prem mitoch you can kind of think the mitochondria is sort of being a factory okay so uh there can be problems in the factory or there can be problems with delivery of things to the factory if you got a factory that's making shoes and there's something wrong with the shoe making machine well then there's something wrong with the factory itself but if you got a factory to make shoes but the trucks that deliver the leather aren't getting there on time then that would be a preact problem so that's kind of how you want to think about these things but premitochondrial problems uh can be decreased lipolysis that means decreased break breaking down of fat this is very common uh hypoglycemia means low blood sugar uh you need sugar to produce energy optimally uh so if your blood sugar is low can't do it esea means a decrease in blood flow this is the kind of thing that would happen when your your circulation is impaired very very common in the over 50 age group hypoxia refers to not getting enough oxygen in your bloodstream uh this can be obvious from smoking cigarettes there's a main way to get hypoxia uh other ways to get hypoxia uh would be if you had a condition like asthma or if you have any other condition of the lungs allergies things like that can lead to hypoxia um carbon monoxide toxicity which is not that uncommon in today's modern buildings can lead to hypoxia uh decreased methylation I will talk about the methylation process in lecture four it's a a somewhat complex uh uh biochemical process but I think every doctor and and patient should really have an idea of what methylation is and uh and inflammation inflammation is a huge topic inflammation will generally uh decrease the ability of the mitochondria to get the get the substrates that they need to produce cellular energy production efficiently and then finally it's the mitochondria themselves mitochondria can become toxic especially heavy metals like lead and cadmium and Mercury can be very toxic to mitochondria stress I'll tell you about the case of a remarkable woman who's 64 years old and the impact of stress on her cellular energy production um nutritional deficiencies this where your B vitamins in particular especially magnesium other enzyme deficiencies this is where they act hormonal deficiencies are a huge problem especially as people get older uh they can impact on the way mitochondria work a mitochondria need certain hormones to function if they don't get those hormones they will not work efficiently and finally decreased phys Fitness so Fitness is an important aspect of keeping your mitochondria up and running so these are sort of the 10 causes on on how people do develop early onset mitochondrial dysfunction and those young people I was telling you about almost all of them the cause was low blood sugar uh and uh because they just ate very poorly and they didn't get enough sleep but but but these overall when I'm measuring my patient's cellular energy production and it's bad I'm going to look for these kinds of causes to start helping them improve uh now diagnosing eomd is important by now you probably started to figure that out and but here's why a little reiteration because through the combined Ox action of increased free radical formation and decreased antioxidant buffering eomd is the primary cause of all of this mitochondrial Decay aging and degenerative disease so if you don't want to have that you don't want to have it aging you don't want to have mitochondrial Decay and you want to get diseased don't get eomd because that's that let's skip right over to this slide does it by a combination of two factors which work together so up here I've listed many of the many of the causitive factors that we just talked about decreased fat metabolism eskee hypoxia Etc all that stuff is right up here okay that leads to decreased mitochondrial function eomd right in here okay now when the mitochondria don't work so well remember you get increased free radical formation but the other side effect of this is that you get decreased free radical buffering enzymes so let me explain this when your body makes free radicals and it will do that healthy bodies make free radicals I'm making free radicals right now as I talk to you when the body makes free radicals is not a big problem like I say our creator took care of of all of this stuff and he made sure that not only do we make free radicals but we also make special enzymes that contain those free radicals so they can't hurt us these enzyme systems are called uh free radical or antioxidant buffering systems you might have heard of some of them like catalases one superoxide dismutases one glutathione peroxidase these are all uh buffering enzymes what these enzymes are able to do is run around find the free radical grab it and neutralize it before it can do any harm and however you got to remember now that these free radical buffering enzymes they're all made from energy so you can't make these enzymes if you don't have adequate amounts of cellular energy production so think of it when you have decreased cellular energy production you get a double whammy on the one side you're producing more and more free radicals because the mitochondria inefficient on the other side because you don't have enough energy production you can't produce enough of the uh uh antioxidant enzyme systems that quch those free radicals you got too many of the bad guys not enough of the good guys that's a double ramming and what that leads to is the mitochondria actually become destroyed over time can take decades but they'll become destroyed a cell that used to have 3,000 mitochondria might have 2,000 by the time that person reaches age 55 and of course as the mitochondria destroyed that decreases the cellular energy production even more and it's just a vicious cycle and so for decades starting in your 30s and working through your 40s and 50s this is this is sort of the Vicious Cycle that's going round and round in your cells decreased cellular energy production increased free radicals decreased ability to quelch those free radicals in increased mitochondrial Decay and aging ultimately the whole system breaks down by the time you're 60 70 you start to actually see breaking down of the body we call that aging and degenerative disease all those diseases that old people get but young people don't get we call that degenerative disease that's how it starts so now you have a sense for why why it's important to know about your production so in summary oxygen is converted to water Plus energy through the process of cellular energy production free radical damage occurs to the mitochondria and inevitably occurs as a result of this process so as you're doing that you're going to get some free radical damage that's why we can't live forever if we never had any free radical damage theoretically our bodies would never break down and we'd live forever but that can't happen and uh so ultimately we will die the problem is because we're making these free radicals in excessively rapid fashion and in excessive amounts and because at the same time we're making too many of them we're not making enough of the enzymes to control them we're aging prematurely we're aging at a much more rapid rate that we need to and we're falling apart at much earlier ages than we need to there's no reason absolutely no reason on Earth why the average age of this of American population could be 10010 and I'm talking a fully functional 100 110 there's no reason the only reason that we don't see that is because of this excessive free radical damage due to a decrease in cellular energy production so Oxygen's converted to water plus energy as that happens we get free radicals this starts to destroy cells the longer you're alive the more damage you're going to get from that and the less efficient the process of cellular energy production the more and the faster that's going to happen as that accumulated free radical damage can continues to worsen it leads to mitochondrial Decay mitochondrial Decay is the central lesion we've seen that it's been published we know this in the entire aging process and in all degenerative disease aging and degenerative disease is is determined by your starting point Genetically speaking how good were you at cellular energy production even when you were born and how well are you taking care of it how rapid has been your rate of eomd my mitochondrial Decay is inevitable sooner or later you're going to get it and you're going to die what's not inevitable is the rate at which that occurs and the rate of mitochondrial Decay is determined by one thing and that is oxidation efficiency or cellular energy production so if you want to slow down aging if you're interested in not getting sick as you get older if you're interested in feeling great and functioning have full function as you get to be older uh then what you want to do is production now I'm going to go over a slide here that shows this thing in kind of a graphic process it shows the stages of the aging process as it relates to Cellular energy production here's a healthy person this right here maximum ATP again ATP is the energy molecule so if this is the maximum at production here's your healthy person he's at the maximum uh now you produce ATP you can produce energy in two ways you can produce it with oxygen and you can produce it without oxygen we know this because if you were to hold your breath your oxygen levels would go down very quickly you wouldn't die instantly would you you'd actually stay alive for a while and the reason you'd stay alive is because your body has a way of producing energy even without oxygen now it's not a very efficient way it leads to a dramatic increase in free radical production and ultimately you'll die so you can't hold your breath forever but you can't hold hold your breath for a a relatively decent amount of time before you do die and that is because your body has the ability to produce energy keep you alive at least for a little bit uh without oxygen at all and that's what this refers to on the slide where it says anerobic here your Anor robic production of energy or ATP is where you produce energy without oxygen now these where it shows glucose which means sugar and fat the only way you can produce energy from glucose and fat is with oxygen so in your Healthy guy here he can produce a lot of energy that much energy in his mitochondria so that's maximum mitochondrial ATP or energy production right here and then on top of that he can produce some additional energy without the use of oxygen you add all that up his total energy production is right there that's a healthy person let's see what happens to that person as he gets older because right in the middle here is the condition I was telling you about eomd this is where he's asymptomatic he may feel really great or he may have what we call functional symptoms those would be symptoms sort of like tiredness maybe headaches maybe allergies things that the doctor says look you know they're they're they nothing you don't have a disease there's nothing really wrong with you it's just that your body is not working as well as you would like it to work we call this functional symptoms uh and and we hear hear those words if you're in my age bracket if you're in your 60s and you complain to the doctor about about something like that he'll usually tell you something well well that's okay you're just healthy for your age what all of that means is you're not healthy but you're not sick and diseased you're in this category but you're moving that way is the point so let's see the very first thing that happens between the healthy guy and the guy that's not quite so healthy is the inability to burn fat efficiently notice that his total energy production from oxygen is maximum mitochondrial production is mitochondria working just as well but when they're working they're relying much more on glucose and a lot less on fat they can't burn fat as efficiently we'll talk about why that is but that's the very first phase that shows up as people move from healthy to not so healthy is they don't burn fat efficiently this leads to two things one is they become overweight start having more fat on their body two is because they burning more and more sugar they start to get low blood sugar your body can't store a lot of low low sugar so if you start burning it very rapidly you're going to run out pretty quickly and so they develop low blood sugar so this is the thing that we normally see in the the young people and of course as you get older is a much higher incidence of this as this continues though what's going to happen is this is this inability to produce energy well from fat is going to lead to a second phase and that's the mitochondria themselves are going to start becoming very dysfunctional they're not going to themselves work very well such that the total mitochondrial production of energy now goes down so it went down for the first time now whereas they can produce energy at least pretty well from glucose if not from fat here uh now they can't produce energy weth of glucose or fat and they're relying more and more on their Anor robic energy production now notice that their total energy production is still the same so they can still go out and do things you know they can ride up the hill and bicycle the same way they used to when they used to be this way but they're not going to do it nearly as efficiently they're going to be producing an abundance of free radicals they're going to be damaging their body they're probably not going to be able to go up the hill in the same time they used to uh but again these are quote healthy for your age people they're asymptomatic they just have early onset mitochondrial dysfunction eventually however the excess of free radical production from all of this leads to this where now the mitochondria actually is starting to get destroyed maximum energy production for the first time goes down now they have mitochondrial Decay they have disease and they're in a irreversible State here can they make this better yeah they can move here can they go all the way from here to here no not with the technology we know today so the idea is to have your self tested have your mitochondrial function tested if you you're already in the healthy column fine great we'll show you some examples of this in the lectures to come of some real people that were like that if you're not then let's talk about what we need to do to move you in that direction so that you don't continue in this downhill course of decreased cellular energy production disease so we've come up with something at the clinic that I call Cellular medicine uh and uh so cellular medicine uh starts off with this kind of thinking all disease and aging starts in the cell with decreased oxidation efficiency or decreased energy production this decrease in oxidation deficiency begins in the 30s when people are asymptomatic but they're not healthy this leads to a decrease in organ function which is the functional symptoms they don't digest as well they get heartburn etc etc they don't really have a disease they're just not working as well and then finally that in the Frailty and the symptoms of the diseasing the diseases of Aging so in my concept here with cellular energy with cellular medicine there's only one disease we're simplifying this and that disease is decreased cellular energy production and there's only one treatment which is maximizing cellular energy production so uh that's why I say that of all the things that I've learned with my patients to help them help their bodies to heal naturally and heal well of all the things I can get them to do improving their cellular energy production is the one that by far and way works the best by the way it's not just for the prevention of disease we've talked here entirely about staying healthy and preventing disease but it's also critical for doctors and patients alike to realize that once you've acquired disease if it takes a lot of energy to prevent a disease how much more energy do you think it takes to actually cure yourself of the disease a lot more so so this becomes crucial and very Central to helping any patient whether the disease is an autoimmune disorder whether it's a chronic infection such as hepatitis whether we're talking about cancer or whether it's heart disease it doesn't make any difference the ability for the body to heal itself of those diseases is is dramatically improved and enhanced when you improve the ability for that body to produce energy on a cellular level uh so that's that's it for part one here um U you can now go to part two or go to it in another time uh the subject we're going to be talking about there is maximizing cellular energy production so we talked a little bit about how cellular energy production uh leads to aging and disease but and we talked a little bit about sort of the things that cause that and so in the next section we're going to talk about how you can maximize your cellular energy production what you can do in your life and what uh your doctors can do to help you and doctors you're going to learn about how to help your patients

Summary: hi I'm Frank shenberger I'm uh I'm a medical doctor I head up the Nevada Center for alternative and anti-aging medicine in Carson City Nevada and I've been practicing medicine for going on 40 years now uh most of that time in excess of 30 years I've devoted to the study of alternative medicine um you can also hear that referred to as integrative medicine or biological medicine or natural medicine basically it's it's when doctors focus on helping uh the pat…


Health, Aging, and Disease - It's all About Energy - Part 3
YouTube video by Dr. Frank Shallenberger (https://www.youtube.com/watch?v=Xa86Euf2cec). Transcript is the auto-caption track — verbatim ASR, not a certified transcript.

hi um I'm Dr Frank shenberger I'm the medical director of the uh Nevada Center for alternative and anti-aging medicine here in Carson City and this uh lecture I'm going to give you is the third part of a four-part lecture series um that is designed to uh teach you about cellular energy production why it's so critically important to your health why it's so critically important to your rate of Aging what you can do about it and in this section we're going to talk about how you can measure it they're going to be some sections in here I'm going to skip through pretty fast because I've already covered them in Parts one and two so if you haven't seen Parts one and two let me suggest that you you look at Parts one and two before you look at part three here um so uh the same of the series is Health aging and disease it's all about energy part one was the importance of cellular energy production part two was how to maximize your cellular energy production and in this part we're going to talk about measuring cellular energy production using a u a very interesting testing uh program that I've developed called bioenergy testing and we'll go into some detail on how that's done and then in the next and final part we'll tell you how you can use bioenergy testing and the results of that test to ma uh to maximize uh your your program to enhance your cellular energy production and and improve your health and actually slow down the aging process um one one of my favorite things I like to say to doctors when I'm giving them lectures is that practicing preventive biological or anti-aging medicine without testing mitochondrial function and as you know by now mitochondrial function is interchangeable with energ cellular energy production so without testing cellular energy production is like practicing Cardiology without being able to test the heart it doesn't make any sense at all the thing that keeps us healthy the thing that slows down aging the thing that prevents disease primarily is cellular energy production and if you can't even test for that you're kind of just operating blindly you don't know what you're doing so being able to test is incredibly important uh and and one of the things I like to also point out to doctors is that you know a lot of people think that therapy is the most important thing in medicine and uh I I would I would at least put up for debate the fact that it's not I will put up for debate for you that therapy is not the most important thing that actually measurement is the most important thing because consider this if you don't have a way to measure what you're doing then you don't have a way of knowing if if what you're doing is actually correct a good example would be a blood pressure we know that blood pressure causes disease uh and yet uh we couldn't even begin to treat blood pressure no matter how many ways we have to treat it we couldn't begin to treat it if we didn't know that number one you had high blood pressure needed treatment and number two if we gave you our treatment we couldn't measure your blood pressure to know that it is in fact working so that's a good example to kind of understand if you don't measure cellular energy production you have no idea if the hormones you're giving if the vitamins you're taking if the exercise you're doing or whatever you're doing is actually doing what you want it to do which is to slow down aging and to prevent Disease by improving cellular energy production so you got to have a testing method uh I've written two books that I'm going to point them out to you here because uh they deal specifically with this topic one book's called bursting with energy uh that is my first B book it deals with energy as it relates to aging the second book is type 2 diabetes breakthrough which deals with energy as it relates to chronic diseases specifically diabetes and both of these books go into much greater detail than this lecture will on everything I'm going to talk about not only that they're fully referenced and they've got all the literature references and scientific references to everything that I'm going to be saying in this lecture those books are available at all the major book Outlets so let's kind of real quick like go through the very Basics here uh this is has been covered in the previous lectures but it doesn't hurt to kind of go over them again uh oxygen is converted to water plus energy that process is called cellular energy production free radical damage to the mitochondria inevitably occurs as a result of that process the longer you're alive the more damage your mitochondria are going to accumulate and the less efficient the process of cellular energy production is the more free radical damage you're going to get this accumulated free radical damage leads to mitochondrial Decay mitochondrial Decay is when the mitochondria or the energy producing systems in the cell are actually destroyed permanently mitochondrial Decay is the central lesion in the aging process and in all degenerative disease we proved that in part one aging and degenerative disease is determined by your starting point that's your genetics basically and by your rate of mitochondrial decay mitochondrial Decay is inevitable you're going to get it ultimately you're going to die haven't figured out a way to stop that yet but what is not inevitable is the rate of Decay how fast that's going to happen that's treatable and that's what we're talking about because mitochondrial Decay rate of Decay is determined by one thing and that's cellular energy production efficiently efficiency so what we're going to talk about today is how to measure that how to know if you in fact are producing cellular energy efficiently uh I pointed this out in the uh in in in the previous lectures cellular energy is different from the energy that you and I normally talk about uh you know we'll talk about I'm having a high energy day or I'm having a low energy day cellular energy production pretty much stays the same every day uh so whether you feel energetic or not doesn't parly out into whether your cellular energy production is high or low uh you can have very efficient cellular energy production and you can feel tired or run down an example of that would be a worldclass athlete who didn't get a good night's sleep on the other hand you can uh feel very good and and have no complaints at all and have very poor cellular energy production so it's incredibly important to measure cellular energy production or you have no idea where you stand um uh I'm going to just very quickly just point this slide out without really covering it it's been covered in the previous lectures uh but the point is that all of these lifestyle things least lead to decreased cellular function as cellular function decreases uh you have increased free radical formation decreased free radical containment that further increases the decreased mitochondrial function and the spin-off is ultimately uh you start aging more rapidly and you start developing chronic degenerative disease this process here starts when you're young and healthy so that's the time to get yourself tested find out if it's going on if it's going on we'll talk about what to do about it so let's define when I'm saying I'm going to test for cellular energy production what am I talking about what am I going to test well one there's basically four things we're going to look at one is resting mitochondrial ATP production so we're going to look at how well you produce ATP is the energy molecule so how well do you produce energy when you're at rest when you're when you're just sitting there I'm basically at rest right now so as I'm sitting here I would like to know how efficiently I'm producing energy so that's one of them and I and we can going to compare it to what's expected so if it's 100 that means it's 100% of what it's expected if it's 150% that means it's 150% of what's expected of course we'd like it to be high uh maximum the other thing we're going to check is maximum mitochondrial energy production that means okay now I'm going to go exercise and I'm going to exercise to the point where my energy production from the mitochondria that means aerobic energy production is at a maximum and I'm going to measure that I'm say well what what's the absolute output I could get if I were a car you might call that the horsepower but what's my maximum energy output that I can get and that's what number two is here so number one is how much energy do I get you sitting here number two is what's the maximum I could do if I'm really forced into doing it number three has to do with fat metabolism and that is as I'm sitting here and I'm producing energy what percentage am I producing from fat and what percentage am I producing from sugar we know that really really healthy people produce more and more their energy from fat in fact in a resting state healthy people exceptionally healthy people produce about 80% of their energy from fat in a resting state and only 20% from glucose now that can be different people that aren't very healthy may may may feel healthy but from a cellular energy production they aren't healthy maybe producing only 20% of their energy from fat uh while they're resting I've seen people that don't produce any of their resting energy production from fat they live entirely off glucose it's not healthy and it's not good but this is what we can see so we want to know how well we're producing energy from fat so we do two ways we look at how well we produce energy from fat when we're resting and then we exercise how well can you produce energy from fat as you exercise and those are the four primary parameters that we're going to look at and evaluate to determine how efficiently our mitochondria are producing cellular energy uh this is a slide that uh we looked at in the in the previous talks and we went into great detail on the first two talks on this slide so uh uh I won't spend a lot of of time on it but just notice and here's the healthy column and here's the maximum energy production from fat as you're moving from Health to disease what's the first thing that happens you don't burn fat as efficiently you rely more and more on glucose second thing that happens is you don't burn either one efficiently and you rely more and more on Anor robic metabolism this is these two conditions are not healthy okay and they can occur in people who feel great who are quote healthy for their age but they're not healthy and then of course the last stage is when they're diseased now this is pretty easy to diagnose doctors can figure this one out but what doctors can't figure out is whether you're in here or not it's kind of like saying doctors can figure out if you have high blood pressure once you've had a stroke but that's that's not what we want to do we want to figure out if you have high blood pressure before you have the stroke so we can prevent you from getting the stroke and from an energy standpoint what we want to be able to do is diagnose you when you're in here you might even feel great but you're not out here you're not sick so how do we know if you're in here the only way you can know that is by looking at these energy production factors that I just mentioned because when you're in here you'll be producing less of your energy from that or you'll be producing total less of here so here's the take-home message uh cellular energy production efficiency is quantita atively measurable in an average clinic setting I've been measuring it my clinic now for 10 or 11 years there are many clinics around the world around the country that are using this testing process you can find out about them by going to www bioenergy testing.com and it lists the clinics that have this this technology more and more clinics are utilizing it all the time and so you just find one of those clinics go in there and get yourself tested um the rate of mitochondrial Decay and hence Aging in degenerative disease is determined by cellular energy production efficiency decreased cellular energy production is caused by known factors that can be manipulated so if you don't test out great fine if you don't test out so great that's fine too because now at least we know you got a problem and we can set about to develop a strategy for you to improve your energy production keep this in mind the decreased cellular energy production begins early in the 30s and the 40s and is asymptomatic the condition I call this is eomd early onset mitochondrial dysfunction and in the first part of this series we went into this a study on this in great detail and finally the efficacy of anti-aging strategies can be assessed by measuring how they influence each individual c cellular energy production efficiency you know when I first got into this field and I've been practicing medicine close to 40 years uh most of those years in excess of 30 have been devoted specifically to preventing disease you know I thought you know this is this is this is a tough deal for a doctor here I am telling my patients to do things to prevent disease and how do I know if it's working well the only way I know if it's working is if they don't get the disease well how am I going to know that I'm going to just have to follow them until they die and see if they get the disease uh that's not really acceptable you mean what's going to happen is a patient's going to come in to see me and I'm going to give them advice on their diet and how to exercise and everything in order to prevent disease and then when they get a disease I'm going to say sorry I guess I was wrong I didn't come up with the right formula for you that's unacceptable so until we had a measure a way of measuring cellular energy production we had no way of knowing if what we're doing is working you can't just go to some study and say look 80% of the people in this study prevented getting Diabetes by doing this because 20% of them it didn't work for we have to find a way to individualize and find out what program for each individual person is going to work for them and the key to that is looking at cellular energy production another way of saying this is whatever program enhances your cellular energy production that's the program you should be on if you're on a program and it's not improving cellular energy production something's wrong and we need to fix it and so it's very critically important for doctors to be able to measure this so how do we do it it's very simple actually um we use an FDA approved pulmonary gas analyzer this this is a device you'll see a picture of it in second where you as you're breathing in and out this device is able to measure how much oxygen is going into your body and how much carbon di oxide is coming out of your body and if you'll remember from some of the uh from the first two parts of this series we we talked in great detail about that's how your cells make energy your cells make energy by converting oxygen into energy and the and a byproduct of that is carbon dioxide so we can actually measure that you can measure how much Oxygen's going in and how much carbon dioxides coming out now we can get that data and then we can analyze it so uh what I've developed here is a computer-driven uh uh no sorry get ahead of myself uh so we have the analyzer that measures the the oxygen in the CO2 out uh then we have a computer-driven exercise ergometer which basically means a exercise bicycle for people to exercise on in a specific rate and then what I developed is this computer software which sorts and analyzes this data when I first started doing this I'd have 20 or 30 strung out feet of computer pages with single line four column data on it and I'd have to sit there for hours and with pen and pencil very carefully we go over and try and and determine how energy production was was being handled uh so uh after a while we figured that's not going to work so we developed a computer program that is able to take that data in a matter of seconds just crank out the algorithms that we need to know to be able to determine how efficiently you're producing energy what do you need you need an exam room it's got to have a table or something people can rest on I happen to use a uh recliner uh you got to have a technician they don't have to be medically trained uh but they do have to be intelligent to work well with people and have some computer skills the test takes about 45 minutes it's easy to do anybody can do it I should I should say almost anybody uh if you're if you have somebody that can't use their legs uh they can't do the exercise part of the test they can still do the resting energy production determinants but they won't be able to work the bicycle so that they couldn't do the exercise part of the determinant so that's how so that's the basic setup uh this is what it looks like uh there's the recliner chair that we use for the resting determination there's the ergometer for the exercise part and here's the unit I didn't make this this is made by a company called medical graphics and these are analyzers in here which are able to analyze how much oxygen is going into the patient how much carbon dioxide is coming out of the patient and then the computer here it takes all of that data tremendous amount of data sorts it analyzes it configures it and then spits out information and just tells us those four factors that I just mentioned to you here's somebody doing the uh resting part that's the device he's breathing entirely through that his nose is plugged up so all the air is going in and out through here and this is being fed into the computer he does that for about seven or eight minutes we then move him over to the bicycle and and uh he does it on the bicycle Accord according to a a very calculated uh uh uh form of exercise so we can just step by step see how well he converts oxygen to carbon dioxide as he's going through the exercise and and that's basically it so so you might wonder well how does it really work how can you determine energy production simply from knowing only two things and it's absolutely fascinating how this can ATP production that's the amount of energy your cells are able to make cellular energy production okay ATP production is directly correlated with oxygen utilization so all that oxygen that you're breathing in only does one thing that's not 100% correct but it's almost 100% correct so maybe I better say Almost 100% of all that oxygen you breathe in only does one thing and that is that it gets converted to ATP so if I can measure with accuracy with an FDA approved device if I can measure with accuracy how much oxygen is disappearing into your body I can make some computations and tell you how much ATP you're making now where does the CO2 come in that comes into further determine that because it gets a little complicated I'm going to show you this in a sec but there's two ways that you can make ATP one is from fat and one is from glucose or sugar uh whether you're making it from fat or glucose that's where you need the carbon dioxide to DET determine because it turns out when you're making energy from glucose you make more carbon dioxide per unit of oxygen than when you make it from fat so by looking at the ratio of oxygen to carbon dioxide I can tell you what percentage of your ATP or energy production you're making from fat and what percentage you're making from glucose and that turns out to be critical based upon what we've been talking about this entire lecture remember from this slide back here this slide back here if you'll remember there's anerobic energy production we don't want to measure that we only want to measure this this is what health is all about we don't want to know this so we want to be able to make the measurement of of energy production and stop it when you become anerobic so how how are we going to tell that we're going to tell that based upon your carbon dioxide production because what happens is as you're exercising on that bicycle your carbon dioxide production is going to go up steady it's going to go up it's going to go up it's going to go up it's going to go up at some point when your mitochondria maximized out and you can't produce any more energy from your mitochondria the CO2 production is going to dramatically climb up now why it's going to do that is because at that point in time the cell since it can't make any more energy from the mitochondria is going to start making the energy anerobic and when it makes it anerobic there's going to be this sudden surgeon lactate because in order to make energy anerobic you have to make a ton of lactate so there's going to be this huge surgen lactate and in the human body lactate immediately gets convered vered to carbon dioxide so what we see as soon as the cell be as soon as the cell gets anerobic there's this dramatic UPS surge in in um in CO2 production and since we're measuring computers measuring CO2 production it's Computing the slope that the CO2 as soon as that slope dramatically changes it stops measuring oxygen consumption so that's how we know that all of the ATP that's being produced that we're measuring all of it is coming from the mitochondria and none of it's coming Anor obic because we shut off the measurement then simply by looking at when that curve happens with CO2 so that's how it happens to recap by measuring all your oxygen in I know how much ATP you're making to measuring CO2 out I know two things one is how much of that ATP is being made from either fat or glucose and two is when you become anerobic and when you become Anor robic I shut the computer immediately stops calculating and that's how we can get all these measurements so let's break down this down a little bit more and give you a little better understanding yet if you don't understand chemistry I still think you'll understand this so bear with me here's glucose here's fat here's a molecule of glucose or sugar and there's six molecules of oxygen so when you get one molecule of glucose with six molecules of oxygen this is what you produce this is what the mitochondria will produce it will produce six molecules of CO2 six molecules of water and 36 whopping molecules of ATP that's a lot of energy there okay from one molecule of glucose 36 molecules of ATP so if we look as far as glucose goes if we look at the amount of ATP you can get from a molecule of glucose at six 36 divided by 6 is six so you get six molecules of ATP for every molecule of oxygen going in when you burn sugar so that the ratio of so if you if you just knew how much oxygen was going in and you knew that that oxygen was only burning glucose you could just multiply it by six and you can get the ATP production so that's how you can get the ATP production when you're measuring oxygen in and you know you're only burning glucose now let's look at that uh fatty acid here with 23 molecules of oxygen produces 60 molecules of carbon dioxide 60 molecules of water and are whopping 130 molecules of ATP a lot of energy produced from a fat molecule a lot of energy in fat if you look at the ratio of ATP to oxygen it's 5.6 so in terms of oxygen you get a you get a little bit less ATP when you burn fat than when you burn glucose again with glucose the ratio was six molecules of ATP per oxygen with that it's only 5.6 molecules of ATP per oxygen so that's why they say the glucose gives you more energy it does more energy per unit of oxygen but fatty acids actually give you more energy but glucose gives you more energy per unit of oxygen so if I knew that you were only burning fat and I knew how much oxygen was disappearing in I could multiply that amount of oxygen by 5.6 and I find out how much ATP you're making so that's how I can tell if you're only burning that I just multiply by 5.6 if you're only Burning uh glucose I multiply by six and I can tell you exactly how much ATP the problem is obvious though at no one time that we're measuring here are you actually burning 100% fat or 100% glucose so how can you possibly tell at any one point in time what you're doing and the answer to that dilemma is exemplified in this next um what we're looking at here is over here's something called respiratory quotient now that is the ratio of uh carbon dioxide to oxygen okay that's over here so I told you those are the only three things we're men measuring and so when the ratio of carbon dioxide to oxygen is 7 that means you're not burning any carbohydrate at all you're only burning fat okay when the ratio is one when there's a one: one ratio between oxygen and carbon dioxide that means you're producing 100% of your energy from carbohydrate and none from fat but look at this it's a perfectly linear relationship which means that any time in here all I have to know is this ratio of carbon dioxide oxygen in and I'll tell you exactly what percentage you're burning for example if I knew the ratio was 085 I come right here whoops 85 is the division point when the ratio is 085 that means half of my energy is being made from fat and half from glucose how about when the energy production is uh when the the ratio of carbon dioxide to oxygen is 75 that means that about 18% of the ATP is being produced from that and the other what 82% is being produced from glucose so that's what's cool and so the computer knows this so the computer knows how much ATP is going in I mean knows how much oxygen is going in and because it can then be determine from the CO2 how much uh whether the oxy what percent of oxygen is going to Fat what percent is going to glucose it can literally sort all that out and tell you precisely how much ATP you're making and that's how the thing works it's rather simple but uh until this date nobody's ever actually put that together um so these are the kinds of things that you learn from that we we already kind of talked about this is the total resting ATP production the resting ATP production from fat the maximum aerobic ATP production the maximum aerobic ATP production from fat so those four we mentioned already but we can also determine a fifth thing called maximum aerobic work which means per unit of oxygen going in how much work does that produce that's a very unique uh determination that as far as I know nobody's ever looked at and what we can tell you is that is a mixture of how well you can produce energy and how well you can harness that energy in your muscles to produce power so this takes into account not only cellular energy production but also how how much muscle mass do you have and that's important because as we get older we tend to lose muscle mass and that this this may be the prare indicator of what rate of Aging you're at I have found that of all of these factors in here the hardest one to get to be normal and people as they get older is this last one right in here and that that would stand to reason wouldn't it also you can get a very good uh uh look at what your biological age is because your biological age is best determined by uh how you match up what age you match up with so let me give you an example uh just right now and then in the next part we're going to go into some a lot of specific examples on how you can use the results of this test to really work with people but I'll just give you a little example right now I'm 62 years old and uh my maximum aerobic ATP production is 130 that means I'm 130% of what would be expected in a 40-year-old man if you match that out it comes out to my biological age would be 34 that means I'm producing ATP with the same efficiency as the average 34 year old man so I would say based upon that my biological age is 34 and that's pretty good and I'm pretty happy about that um it's not by accident of course you know I've used the results of this test on myself for many many years to try and fine-tune my physiology to uh get me get my to the point that it's producing energy with that level of efficiency and again in the next part we'll talk more about how you can actually use this data in your practice uh to help help your patients uh achieve a very functionally and efficiently program but you can also learn more some some stuff that's really valuable you can learn uh what your patient's optimal exercise zone is uh remember we talked about how important it is to exercise but we also talked about how important it is to exercise correctly if you don't don't exercise hard enough you're not getting enough bang for your book and if you exercise too hard you're going to be damaging yourself and so you know we published a study maybe five years ago in the Townson letter uh where we looked at 20 patients who were going to gyms and receiving trainings from trainers there on how to exercise aerobically there were were based upon formulas and uh these these people were advised to reach such certain heart rate for such a period of time Etc while they were doing their aerobic exercise of the 20 people that we checked 18 of them were exercising way too hard for what their mitochondria were able to deal with in other words the trainers had used these formulas which are absolutely ridiculous formulas they don't work at all they're meaningless I don't even know why people buy use them anymore uh but trainers would use these formulas to establish an exercise protocol for these patients and in 18 out of the 20 cases the exercise protocol they had the people doing was actually harmful to them um so if you want to prescribe exercise for your patient in a way that's helpful in a way that maximizes cellular energy production it's pretty critical to be able to measure what their actual exercise zones are because these formulas are useless to determine that and you can get that precisely in each individual patient just from the bio energy testing report uh if if a patient has any issue with calorie intake in other words if they need to lose weight uh you can know their exact calorie intake another another batch of formulas that is pretty much essentially useless to figure out what is is the formulas that are used to determine calorie intake so what you can do is you can go to one of the books and you can say okay you're a male you're this uh you're this weight you are this tall and this is what your daily calorie expenditure is it's never that it's it's always actually a lot less than that those formulas are just useless today don't ask me why I'm just telling you they are because when we actually compute how many calories they're burning sitting there Andor exercising we find that it's very much different from what the uh tables and the books tell us so we don't have to guess at exercise Zone we don't have to guess at caloric intake we know exactly the caloric int take now many of you that are in the anti-aging specialty know that one of the Premier ways to make sure that your aging is uh aging process is slowing down is to limit your calorie intake you can't do that if you don't know how much calorie you're supposed to be taking so that's another way calories can be used to establish a protocol of uh diminished calorie intake for longevity purposes uh what we found out by the way in doing this is that almost everybody almost everybody uh whether they're skinny or not it doesn't make any difference almost everybody totally overeats and it's only by doing this uh study here that you can learn whether or not you're overeating because you can't tell by whether you're skinny if you have a rapid metabolism you can be overeating and still be skinny uh but you can also get a cardiac output that's very important for doctors to know you can get get a pulmonary function uh so that tells you all about your heart and your lungs um we can also determine what the optimal carbohydrate intake is how can you determine that it's actually quite simple if you see that resting fat metabolism is depressed we know that almost always the re the way reason resting fat metabolism is depressed is from excessive intake of carbohydrate so how do you determine that you get a resting fat metabolism you then put the patient on a lower carbohydrate diet you come back and retest their resting fat metabolism if it's lower you've just proven to yourself that they're taking in too many carbohydrates and by using that technology you can actually very easily determine what the optimal carbohydrate intake is for everybody in other words whether they're fast or slow oxidizer just where are they on that Spectrum this is invaluable data to help your patients uh lastly I I mentioned is here there there's every now and then we pick up somebody that has Subacute hyperventilation uh this can be an issue with various asthma States and various anxiety and insomnia States uh the test can pick that up so whereas these are much more valuable from a percentage standpoint uh that is a nice thing to every now and then we pick up somebody on that so that that's the kind of data that you can learn uh the way doctors the way I use this in my practice is very simple it's very obvious uh patient comes comes in I I get a complete history and physical examination absolutely indispensable for being able to learn more about my patient I then uh have them do the bioenergy Test Plus appropriate specific testing this would be the standard test that doctors do um so when they walk in my door I have this available to all that information we just went over it's in my hand I have the I know all about them and I have all other appropriate testing like what their blood sugar is and what their hormone levels are and so forth I immediately can come up with a treatment plan that's that includes this is how you exercise this is how you eat this is how you sleep um uh these are the supplements you need to take these are the hormones you need to take I come up with a very comprehensive treatment plan in a matter of minutes and that treatment plan is geared to their cellular energy production so there's my treatment plan how do I know it's working though maybe I didn't do a very good job most most of the time I do but quite frankly every now and then when we repeat the bioenergy testing uh say uh 3 four five months later what we find out is it wasn't that it was approved but it wasn't that great which case we kind of go back and remodify that's down here so we repeat it it's not improved we do maybe some specific testing remodify and we keep going through this process until it pops out that it's improved and we're at optimal levels of cellular energy production and then I know that that program is suited for that patient to get the result that I want it to get and I don't have to wait to see if they get sick because I know that we can't do anything better to prevent disease in that person than we've already done by production so um who should have bioenergy testing pretty much everybody that should be obvious by now anybody who exercises should every person who complains of low energy tiredness or has any issues with weight should everybody over the age of 40 unless they don't want to develop a scientifically individualized program to prevent disease and slow aging if they're not interested in that well they shouldn't do it but everybody else everybody who's battling a disease again and I mentioned this before if it takes a lot of energy to stay well it takes even more energy to get well and so it's very important for patients who are battling disease to have their uh cellular energy production tested when okay when should a patient not be tested well every patient you see regardless of health status should be T tested doctors should ask yourself this question when would you not want to know your patient's cellular energy production given all the data that's out there all the compelling scientific information and research that points to Cellular energy production being at the very core and center of why we age and get sick why would you not want to know how your patients doing that or yourself for that matter the outcome of all diseases is improved by the enhancement of mitochondrial function the thousands of studies that point this out all cause mortality has been shown in a number of studies to be decreased by maximizing cellular energy production and all successful prevention and anti- aging programs have to be based upon optimal seller energy uh production so when we you should a patient not be tested I can't think of an incidence except for maybe an acute heart attack or some reason why they can't exercise and even then they can do the resting part of it so the take-home message here eomd which is a decrease in cellular energy production is it's for real this happens early when you're young it happens commonly and so-called healthy individuals you won't know it just by looking at your symptoms or your lab test it causes premature aging degenerative disease all cause mortality it can be diagnosed easily and accurately using this testing process it can be reversed that's the best part why diagnose it if you can't do anything about it and it is diseases so um that that's the end of this uh section we have one more section to this lecture series it's going to be part four and it's going to the how to use bioenergy testing results thing we just talked about to maximize health and to slow down aging we're going to actually go through some case examples and work our way through how to interpret the information and what it leads doctors to be able to do uh so

Summary: hi um I'm Dr Frank shenberger I'm the medical director of the uh Nevada Center for alternative and anti-aging medicine here in Carson City and this uh lecture I'm going to give you is the third part of a four-part lecture series um that is designed to uh teach you about cellular energy production why it's so critically important to your health why it's so critically important to your rate of Aging what you can do about it and in this section we're going to…